Ototoxicity of Capreomycin

Capreomycin-induced serum electrolyte abnormalities.

Objective Measures of Ototoxicity

A leading cause of preventable sensorineural hearing loss is therapeutic treatment with medications that are toxic to inner ear tissues, including certain drugs used to fight cancer and life-threatening infectious diseases. Ototoxic-induced hearing loss typically begins in the high frequencies and progresses to lower frequencies as drug administration continues (Campbell & Durrant, 1993; Campbe...

Capreomycin Powder for Inhalation in Guinea Pigs

28 Anthony J. Hickey 29 University of North Carolina at Chapel Hill, 1310 Kerr Hall, CB #7360, Chapel Hill, NC 3

Ototoxicity of toluene in rats.

Toluene is a major industrial solvent and substance of abuse which is ototoxic in rats as shown by both behavioral testing and measurement of brainstem auditory evoked response (BAER) thresholds. The objective of this investigation was to examine the morphological (hair cell loss) and functional (BAER threshold elevations) changes resulting from toluene administration. In the preliminary experi...

Editorial: Cellular Mechanisms of Ototoxicity

Oregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States, National Center for Rehabilitative Auditory Research, VA Portland Health Care System, Portland, OR, United States, National Institute on Deafness and Other Communication Disorders, Bethesda, MD, United States, Hearing Center of Excellence, J-9, Defense Health Agency, Joint Base San Antonio, San Anto...